Nedsatt konsentrasjon av zopiklon. Basert på information fra andre kraftige induktorer av CYP3A4 må man regne med at konsentrasjonen av zopiklon kan synke med i størrelsesorden 80 %. The risk is greater Should the medication is taken lengthier than the usual few months or stopped abruptly, in place of progressively reducing the dose. [3] S

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